Developmental profile of SK2 channel expression and function in CA1 neurons
نویسندگان
چکیده
منابع مشابه
SK2 channel expression and function in cerebellar Purkinje cells.
Small-conductance calcium-activated K(+) channels (SK channels) regulate the excitability of neurons and their responsiveness to synaptic input patterns. SK channels contribute to the afterhyperpolarization (AHP) following action potential bursts, and curtail excitatory postsynaptic potentials (EPSPs) in neuronal dendrites. Here we review evidence that SK2 channels are expressed in rat cerebell...
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متن کاملDevelopmental regulation of small-conductance Ca2+-activated K+ channel expression and function in rat Purkinje neurons.
Calcium transients play an important role in the early and later phases of differentiation and maturation of single neurons and neuronal networks. Small-conductance calcium-activated potassium channels of the SK type modulate membrane excitability and are important determinants of the firing properties of central neurons. Increases in the intracellular calcium concentration activate SK channels...
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ژورنال
عنوان ژورنال: Hippocampus
سال: 2011
ISSN: 1050-9631
DOI: 10.1002/hipo.20986